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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
15.45
Human Site:
S232
Identified Species:
22.67
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
S232
E
T
D
S
S
S
A
S
A
A
T
P
S
K
K
Chimpanzee
Pan troglodytes
P60051
493
55922
S232
E
T
D
S
S
S
A
S
A
A
T
P
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
K204
S
A
A
T
P
S
K
K
K
S
L
I
D
Q
F
Dog
Lupus familis
XP_537306
545
61461
S283
E
T
D
S
S
S
A
S
A
V
T
P
S
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
P232
E
T
D
S
S
S
A
P
A
V
T
P
S
K
K
Rat
Rattus norvegicus
NP_001008302
493
55958
S232
E
T
E
S
S
S
A
S
A
V
T
P
S
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
K177
A
A
A
P
P
K
K
K
S
L
I
D
Q
F
F
Chicken
Gallus gallus
XP_419150
492
55612
A230
V
M
E
T
D
S
G
A
T
A
T
A
S
K
K
Frog
Xenopus laevis
Q6GNI6
523
60030
E228
E
M
S
T
L
F
Q
E
F
Y
S
G
H
R
S
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
H236
L
V
W
T
H
A
R
H
L
A
G
Y
E
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
S219
R
P
K
N
Q
E
P
S
N
T
V
Q
K
R
H
Honey Bee
Apis mellifera
XP_395043
497
56311
N227
K
E
N
L
A
S
E
N
N
G
Q
S
Y
K
P
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
L209
N
V
T
R
I
Y
G
L
S
G
W
N
I
E
S
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
A233
P
A
V
E
G
A
P
A
A
A
G
A
V
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
S212
L
L
Y
T
L
S
Q
S
L
K
A
P
T
S
S
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
F218
E
E
L
F
T
Q
L
F
H
S
M
S
I
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
86.6
N.A.
0
40
6.6
6.6
N.A.
6.6
13.3
0
20
P-Site Similarity:
100
100
26.6
93.3
N.A.
86.6
93.3
N.A.
6.6
60
26.6
33.3
N.A.
20
40
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
19
13
0
7
13
32
13
38
32
7
13
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
0
7
0
0
0
0
0
0
7
7
0
0
% D
% Glu:
44
13
13
7
0
7
7
7
0
0
0
0
7
7
0
% E
% Phe:
0
0
0
7
0
7
0
7
7
0
0
0
0
7
19
% F
% Gly:
0
0
0
0
7
0
13
0
0
13
13
7
0
0
0
% G
% His:
0
0
0
0
7
0
0
7
7
0
0
0
7
0
7
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
7
7
13
0
0
% I
% Lys:
7
0
7
0
0
7
13
13
7
7
0
0
7
44
44
% K
% Leu:
13
7
7
7
13
0
7
7
13
7
7
0
0
0
0
% L
% Met:
0
13
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
0
7
7
0
0
0
7
13
0
0
7
0
0
0
% N
% Pro:
7
7
0
7
13
0
13
7
0
0
0
38
0
0
7
% P
% Gln:
0
0
0
0
7
7
13
0
0
0
7
7
7
13
7
% Q
% Arg:
7
0
0
7
0
0
7
0
0
0
0
0
0
13
0
% R
% Ser:
7
0
7
32
32
57
0
38
13
13
7
13
38
7
19
% S
% Thr:
0
32
7
32
7
0
0
0
7
7
38
0
7
0
0
% T
% Val:
7
13
7
0
0
0
0
0
0
19
7
0
7
7
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
0
0
7
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _